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Controlling Sample Temperature during Bead Milling using Passive Cooling with the new 7 mL Carriage

August 5, 2024

Bead Mill technology has become a forefront in sample preparation for a variety of sample matrices. From tissues, bone, soil, and microbes, bead milling is one of the quickest and most efficient ways to disrupt samples for scientific analysis. Bead mill homogenizers, such as the Omni Bead Ruptor Elite™ bead mill homogenizer, function by vigorously shaking tubes containing dense bead material to disrupt samples. The impact between the beads and the sample reduces the sample particle size and creates a homogenous mixture. While bead milling is an efficient method for homogenization, for some, the addition of the bead media can be a drawback. The kinetic energy that is generated by movement of the beads within the tube and sample material increases sample temperature. In some cases, heat sensitive analytes can be affected. Herein we evaluate intra tube temperature after processing on the Omni Bead Ruptor Elite bead mill homogenizer coupled with the new 7 mL Tube Carriage. 

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Figure 1. The temperature readings of the five experiments are plotted above.

 

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